Why Having a Purpose in Life May Protect You From Alzheimer’s

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Recent studies have shown that having a strong purpose in life can prevent cognitive decline even in people whose brains show evidence of Alzheimer’s. Here’s how you can protect your brain and increase your life satisfaction at the same time.

I just finished Life Reimagined: The Science, Art, and Opportunity of Midlife  by Barbara Bradley Hagerty. It’s a fascinating book: full of tips on how to navigate midlife as we lay the groundwork for transitioning to the second half of our lives. She shares a lot of good information that I enjoyed reading – particularly about the importance of working to maintain our friendships as we age – but the most important information I got from her book was something I had never read before: when it comes to Alzheimer’s, the disease that rightly strikes fear in the heart of every midlife person, biology is by no means destiny. 

What is Alzheimer’s Disease Anyway?

Alzheimer’s is not synonymous with dementia; it’s just one of several conditions that may cause dementia as we age. It is thought that Alzheimer’s is caused by changes in the brain that result in abnormal clumping of brain cells (called amyloid plaques) and twisted brain fibers (called neurofibrillary tangles).

Although your doctor may diagnose you with Alzheimer’s based on your symptoms such as memory problems (and shockingly, losing your sense of smell), a true diagnosis of Alzheimer’s cannot be made without an autopsy after death. Only then can it be determined whether your brain has the clumping and twisting associated with Alzheimer’s.

Watch this video on YouTube.

Studies Suggest Hope for Alzheimer’s Patients

If Alzheimer’s is caused by your brain actually degenerating so it can’t work properly, then it’s easy to assume that there’s really not anything we can do to prevent memory loss once the brain starts changing.

However, a recent study of older people suggests otherwise. This study followed people who agreed to have their cognitive abilities tested as they grew older and then have an autopsy performed to test for Alzheimer’s when they died (still the only way to truly diagnose the disease). To the amazement of the researchers, they consistently found that at least a third of the subjects with the distinctive plaque that is a marker of Alzhimer’s showed no mental impairment during their lifetimes. 

Why Do Some People with the Plaque Associated with Alzheimer’s Stave Off the Symptoms of the Disease?

So what protected these people from their supposedly inevitable mental decline? Was it regular exercise, good nutrition, good music and a good woman as my dad might have said? Well, those things helped, but the number one attribute people who escaped dementia had in common was a purpose in life. 

Each study participant was evaluated from time to time on their general life satisfaction and whether they felt their life had value and meaning. Study participants who scored at least 4.2 out of 5 on the test that evaluated whether they felt a purpose in life were around 2.4 times more likely to remain free of Alzheimer’s symptoms than did those participants who only scored a 3 out of 5.

This means that these folks not only felt like they had a purpose in life, they felt that they had strong purpose in life. They believed (accurately, I’m sure) that their lives had meaning and value.

These participants also had a lower incidence of mild cognitive decline, the precursor to Alzheimer’s.

It might have been Saturday morning language lessons, or a passion for race walking, or even a strong love for their grandchildren but these folks had a reason to get up every day and so they were motivated to keep their brains sharp to continue to enjoy their passion. They were so motivated by what they loved that their brains compensated for the damage caused by the plaque growing on it from Alzheimer’s. Their brains overcame their destiny. 

Watch this video on YouTube.

What’s Your Purpose in Life?

That’s powerful stuff. And encouraging. Because if you’re in midlife now, this is the perfect time to find or start enjoying your passion. Your mind may depend on it. 

I don’t know what test the researchers used to determine whether the study participants had a strong purpose in life, but I found this test which seems to measure something similar.

If you’re having trouble determining what your purpose in life should be or feeling like you don’t even know yourself any longer, you might enjoy my ebook 10 Days to Rediscover Yourself after the Children are Grown. It’s filled with exercises to help you rediscover your likes and dislikes and think about what you really want from this next phase of your life. I think you’ll enjoy it.

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Katy Kozee | Midlife Rambler

Hi! I'm Katy and I started Midlife Rambler when my youngest child was a senior in high school. I was staring at the coming empty nest and wondering what was next for me. Does that sound like you? Then you’ll love our community of fun, feisty women. We’re looking forward to finally focusing (just a little) on ourselves and talking about all the things we enjoy: fashion, beauty, travel, entertaining, and being the best possible you.

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13 thoughts on “Why Having a Purpose in Life May Protect You From Alzheimer’s”

  1. Great post! My children tease me about how many times I’ve retired, but keep going back to part-time work! I love interacting with people and I work for” Visiting Angels”. Only 12 hours a week but it is soooo rewarding and keeps me active, in body and spirit.

  2. This makes sense to me, and is something I think about a lot. We are living longer and once the kids are gone and our career starts to wind down, its time to ask ‘what’s next?’ I think i’ll get the book, sounds like a good read.

    • Yes, we’re really not retiring these days as much as we’re just moving on to our second career. You should definitely get the book – it’s fascinating.

  3. What interesting information! A purpose in life. I knew it was important but I didn’t know it was that big of a deal. I’m glad I found out now so I don’t waste the rest of my life binge-watching Netflix. Wait. Is that a purpose?

    • If you binge watch and then blog about it, it can become your purpose! Kinda like I did with sitting around reading 🙂

  4. My grandmother lived to be 96 and sharp that the end. She played the piano in church every Sunday and I have always believed that her commitment to that kept her sharp and tuned in to life.

    • I’m sure it did. I’ve read other studies about how music in particular keeps your brain sharp. How lucky you were able to have your grandmother for so long.

  5. So true! Keep the brain active. We just had my husband’s 97-year-old grandmother visiting us and we took her to New York City for the weekend because she was begging us to do so. She walked all around, laughed, talked to everyone, spend time with my grown daughters there! She has always had a purpose and is a true inspiration. Still drives, cooks, and plays bridge several times a week. Great post!

  6. Interesting post – I can see how keeping a purpose in life would help. Ok- so I won’t stop the renlentless pursuit of becoming so wealthy that I can sit around doing nothing (except that after reading this, when I get there, I won’t sit around doing nothing after all!) 🙂


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